Treatment during pregnancy
The NICE guideline (2013) recommends
» Tenofovir is offered to pregnant women with HBV DNA levels >10 E7 IU/ml in the third trimester to reduce the risk of HBV transmission to the baby
» HBV DNA levels should be checked two months after starting tenofovir and the ALT levels should be checked monthly after birth to detect postnatal flares
» Treatment can be discontinued 4-12 weeks after delivery, unless the mother meets the criteria for long-term treatment
» Mothers may breastfeed while taking antiviral therapy.