Clinical Studies
In a study at Brown University School of Medicine, the intake of AGE lowered cholesterol levels and blood pressure in men with high cholesterol levels, men received AGE at a dose of 800 mg/day, for six months, followed by placebo for four months. Cholesterol levels and blood pressure were measured monthly. Results showed that total cholesterol levels fell by an average of six to seven percent and that systolic blood pressure decreased by 5.5 percent; there was a smaller decrease in diastolic pressure.
A breakthrough clinical trial from the University of California in Los Angeles, by M. Budoff, MD and colleagues, found a dramatic reduction in coronary artery plaque formation in AGE treated patients compared to placebo and, among the other multiple cardioprotective effects a reduction in blood pressure.
AGE Effective Where Anti-Hypertensive Drugs Failed Investigators at the University of Adelaide in Australia showed for the first time that AGE can treat hypertension more effectively than medication. The study, published in 2010 in the Journal Maturitas, was a randomized, double-blinded placebo controlled trial of 50 patients whose high blood pressure did not respond to anti-hypertensive drugs.
The patients were adults with systolic blood pressure of 140 mm Hg or higher and diastolic pressure of 90 mm Hg or above. They were all being treated with conventional antihypertensive medications and instructed not to change the prescribed medications during the trial. Twenty five patients received four capsules a day, containing a total of 960 mg of odorless AGE and 2.4 mg S-allyl cysteine, for 12 weeks. This daily dose was equivalent to an intake of 2.5 mg of fresh garlic. Twenty-five control patients received a placebo of similar capsules, devoid of AGE. Blood pressures were monitored at baseline and at 4.8 and 12 weeks. Patients were reminded to keep taking their usual prescribed antihypertensive medicines.
AGE as an Adjunct Treatment
Clinical StudiesIn a study at Brown University School of Medicine, the intake of AGE lowered cholesterol levels and blood pressure in men with high cholesterol levels, men received AGE at a dose of 800 mg/day, for six months, followed by placebo for four months. Cholesterol levels and blood pressure were measured monthly. Results showed that total cholesterol levels fell by an average of six to seven percent and that systolic blood pressure decreased by 5.5 percent; there was a smaller decrease in diastolic pressure.A breakthrough clinical trial from the University of California in Los Angeles, by M. Budoff, MD and colleagues, found a dramatic reduction in coronary artery plaque formation in AGE treated patients compared to placebo and, among the other multiple cardioprotective effects a reduction in blood pressure.AGE Effective Where Anti-Hypertensive Drugs Failed Investigators at the University of Adelaide in Australia showed for the first time that AGE can treat hypertension more effectively than medication. The study, published in 2010 in the Journal Maturitas, was a randomized, double-blinded placebo controlled trial of 50 patients whose high blood pressure did not respond to anti-hypertensive drugs.The patients were adults with systolic blood pressure of 140 mm Hg or higher and diastolic pressure of 90 mm Hg or above. They were all being treated with conventional antihypertensive medications and instructed not to change the prescribed medications during the trial. Twenty five patients received four capsules a day, containing a total of 960 mg of odorless AGE and 2.4 mg S-allyl cysteine, for 12 weeks. This daily dose was equivalent to an intake of 2.5 mg of fresh garlic. Twenty-five control patients received a placebo of similar capsules, devoid of AGE. Blood pressures were monitored at baseline and at 4.8 and 12 weeks. Patients were reminded to keep taking their usual prescribed antihypertensive medicines.AGE as an Adjunct Treatment
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