Antibacterial activity against P. aeruginosa was detected
only at high concentrations matching the low sensitivity of
the essential oil against Gram-negative bacteria, as previously reported by several authors [18–20]. However, at the above concentration, the oil showed significant cytotoxic effects in
vitro toward keratinocytes, thus making in vivo topical application against P. aeruginosa infections improbable. The antibacterial activity of the essential oil may be due at least partly to α-pinene and E- and Z-citral. The less abundant