Administration
Should be taken with food. GI discomfort may be reduced by increasing the dose of l-dopa gradually, &/or by taking w/ or after meals. However, taking l-dopa on a full stomach may lead to lower plasma conc. In later disease, it may be preferable to admin on an empty stomach if the patient can tolerate it. Keep a consistent diet. A change in diet to foods high in protein may delay l-dopa absorption & reduce amt taken up in circulation.