CONCLUSION
The recently published articles concerning epidemiology
and risk factors of ASB and UTI in diabetic and
pregnant women mainly confirmed existing knowledge.
Adverse effects of treatment of diabetes
mellitus and bacteriuria itself were emerging topics.
The newly developed type 2 diabetes mellitus
agents, SGLT2 inhibitors, were found to be associated
with a small increased risk for UTI due to
increased glucosuria. In addition, antibiotic treatment
of ASB or UTI during pregnancy was related to
short-term and long-term consequences in the neonate.
In the light of the possible adverse effects of
antibiotics, more studies exploring the possibilities
for non-antibiotic interventions to prevent or treat
ASB and UTI are needed. Moreover, evidence regarding
optimal treatment of UTI in diabetic patients is
still lacking. Also, up-to-date studies investigating
whether screening and treatment of ASB is still
useful (including GBS bacteriuria during pregnancy)
are necessary to inform clinical practice.
CONCLUSIONThe recently published articles concerning epidemiologyand risk factors of ASB and UTI in diabetic andpregnant women mainly confirmed existing knowledge.Adverse effects of treatment of diabetesmellitus and bacteriuria itself were emerging topics.The newly developed type 2 diabetes mellitusagents, SGLT2 inhibitors, were found to be associatedwith a small increased risk for UTI due toincreased glucosuria. In addition, antibiotic treatmentof ASB or UTI during pregnancy was related toshort-term and long-term consequences in the neonate.In the light of the possible adverse effects ofantibiotics, more studies exploring the possibilitiesfor non-antibiotic interventions to prevent or treatASB and UTI are needed. Moreover, evidence regardingoptimal treatment of UTI in diabetic patients isstill lacking. Also, up-to-date studies investigatingwhether screening and treatment of ASB is stilluseful (including GBS bacteriuria during pregnancy)are necessary to inform clinical practice.
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