Other medications
There is no available information about the effects of antidepressants, anticonvulsants or benzodiazepines on psychiatric and behavioural symptoms. It has been suggested that clonazepam may be helpful in controlling the characteristic sleep disturbance of DLB with its vivid dreams and a loss of normal muscle atonia in rapid eye movement sleep, which lead to excessive jerking or complex vigorous movements. Although limited levodopa responsiveness has generally been reported in DLB, this may reflect a failure to treat, or underdosage, because of concerns about exacerbating psychotic symptoms. A cautious trial of levodopa is recommended in DLB patients with clinically significant motor disability.