By car[edit]
From Bangkok, one can get to Ayutthaya by various routes:
Take Highway 1 (Phahon Yothin) via Pratu Nam Phra In and turn into Hwy 32, then turn left to Hwy 309 to Ayutthaya.
Take Hwy 304 (Chaeng Watthana) or Hwy 302 (Ngam Wong Wan), turn right into Hwy 306 (Tiwanon), cross Nonthaburi or Nuanchawi Bridge to Pathum Thani, continue on Hwy 3111 (Pathum Thani–Sam Khok–Sena) and turn right at Amphoe Sena into Hwy 3263 to Ayutthaya.
Take Hwy 306 (Bangkok–Nonthaburi–Pathum Thani), at Pathum Thani Bridge Intersection, turn into Hwy 347 and Hwy 3309 via Bang Sai Royal Folk Arts and Crafts Centre, Amphoe Bang Pa-in, to Ayutthaya.
Take Expressway No.9 (Si Rat Expressway) via Nonthaburi–Pathum Thani and down to Hwt 1 via Bang Sai Royal Folk Arts and Crafts Centre, turn left onto Hwy 3469 towards Bang Pahan and turn right at Worachet Intersection to Ayutthaya.
One can also contact a taxi for pick up at Bangkok's airports. For example: Car Service, phone: +66 28 195 390, email: raksacharoen@hotmail.com. Advance booking possible. ~1,200 baht one-way.