The main contribution of this paper is a method of mapping 3D content representations to domain-specific ontologies. The method is a key part of the generic approach to Semantic Modelling of Interactive 3D Content (SEMIC), which has been partially described in the previous works10,11,12,13. The method enables mapping of components and properties, which are specific to 3D content, to concepts included in domain-specific ontologies, which may be abstract in the sense of their presentation. Hence, the method enables conceptual content creation at different levels of abstraction, which may be determined by common, reusable concepts. The conformance to the semantic web standards and the possible use of various domain-specific ontologies and knowledge-bases can facilitate content creation and management (indexing, searching and analysing) by domain-experts in diverse application domains.