ith a
backpack filled with 20 kg of sand in order to simulate regular
weight burden. EHST duration was maximally 90 min; the
criteria for termination were: tympanic temperature (Tty)
39.5ºC 10, heart rate (HR) 190 beats/min, or intolerable subjective discomfort. The subjects were allowed to drink tap water
at will, up to 1.5 L. Blood samples were collected before the
EHST and immediately after it.