This report highlights the seriousness of TTX poisoning and its potential to be life threatening. Physicians should have sufficient knowledge regarding the clinical manifestations, complications and management of TTX poisoning. People should be made aware of the potential risk of eating the eggs of C. rotundicauda, about the warning symptoms and signs of poisoning, and when to seek medical help. All but the mildest cases should be admitted to the hospital for close observation. After 24 hours it is unlikely that life-threatening conditions will occur in patients who have not already developed severe effects.