New recipes
For example, the centre of its Butterfinger bars will now have annatto, which comes from the seeds found in the fruit from the achiote tree, instead of certified colours Red 40 and Yellow 5, it said in a statement on Tuesday.
"In CRUNCH, natural vanilla flavour will replace artificial vanillin."
The company is making changes to more than 75 recipes, said health and wellness manager Leslie Mohr, who added that consumer testing had been done on the new recipes.
More than 60% of Americans said the absence of artificial colouring or flavouring was an important factor in their decision to buy food, according to a recent Nielsen survey the company cited.
Nestle is also in the process of removing caramel colouring from its chocolate products.
The new products are expected to be available for sale by the middle of next year.