The recognizing and sensing of anionic analytes have recently
emerged as a key research topic in the field of supramolecular
chemistry because of anions’ important roles in biological, medical
and environmental processes [1–4]. In particular, the selective sensing
of fluoride ion has attracted growing attention due to its significant
function in preventing dental caries and treating osteoporosis [5–7].
For the sensing mechanism, either the specific lewis acid–base
interaction or designed hydrogen bonding is usually adopted [8,9].
Currently available methods for detection of fluoride ion include
spectrophotometry, electrochemistry, ion chromatography, etc. [10–
12]. Presently, a number of compounds that were able to bind fluoride
ion with high affinity and selectivity have been reported [13–15];
however, the challenges of selecting these receptors that would allow
the naked-eye-detection of fluoride ion without resorting to any
spectroscopic instrument still remain [16,17].
The recognizing and sensing of anionic analytes have recentlyemerged as a key research topic in the field of supramolecularchemistry because of anions’ important roles in biological, medicaland environmental processes [1–4]. In particular, the selective sensingof fluoride ion has attracted growing attention due to its significantfunction in preventing dental caries and treating osteoporosis [5–7].For the sensing mechanism, either the specific lewis acid–baseinteraction or designed hydrogen bonding is usually adopted [8,9].Currently available methods for detection of fluoride ion includespectrophotometry, electrochemistry, ion chromatography, etc. [10–12]. Presently, a number of compounds that were able to bind fluorideion with high affinity and selectivity have been reported [13–15];however, the challenges of selecting these receptors that would allowthe naked-eye-detection of fluoride ion without resorting to anyspectroscopic instrument still remain [16,17].
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