Reactive Oxygen Species (ROS) are generated via normal metabolic processes or as the products
of exogenous insults. They are capable of damaging essential biomolecules and accelerating cancer,
cardiovascular diseases and neurodegenerative diseases. In this study, the effect saponin from Solanum
anguivi (SAS) fruits on Superoxide Dismutase (SOD), catalase (CAT) and Lipid Peroxidation (LPO) in the
homogenates of the hearts and kidney was evaluated. Thirty six male Wister rats of average weight125±12
g were divided into six groups of six animals each. Five treated groups received a daily dose of saponin at
20, 40, 60, 80 and 100 mg/kg respectively, while distilled water was administered to the control group for 3
weeks. Solanum anguivi saponin significantly increased (p