Tumors of the CNS are the leading cause of death
for all childhood cancers [ 1 ]. Children living
with incurable brain tumors (BT) follow an
expected and progressive trajectory of multiple
symptoms and loss of function resulting in a high
symptom burden that is distinct from other childhood
malignancies. The purpose of palliative
care is to optimize quality of life, minimize distress
and ease suffering to those children with
incurable malignancy and their families throughout
the course of illness, and not reserved for the
period at EOL. The intent of this chapter is to
provide a review of the salient issues of palliative
care for children with brain tumors.