tance of mosquito-bite prevention, recommendations by public health authorities in some of the most severely affected countries to delay nancy, and advisories that pregnant women avoid travel to areas with virus transmission." However, communications regarding zika virus have been challenging: a recent survey showed low levels of knowledge and concern about Zika virus in the United States. The recognition of Zika virus as a cause of microcephaly and other serious brain anomalies would allow for more direct communication which might lead to improved understanding of and adherence to public health recommendations. Therefore, a review of the evidence linking Zika virus infection and adverse pregnancy and birth outcomes is needed