After treatment with the IC50concentration of DCM and MeOH
extracts, treated cells demonstrated degrees of morphological
changes with observable fragmented nuclei, indicating signs of
apoptosis induction (Fig. 3). Their severity effects were ranked:
HL-60 > MCF-7 > Caco-2 cells, which correlated well to their in-duced anti-proliferation effects. The DNA fragmentation was also
revealed by gel electrophoresis of treated cells (Fig. 4). The results
clearly suggested that apoptosis induction was more potent in HL-60 cell than MCF-7 cell and Caco-2 cell.