An indirect method is presented here for estimating the plasma LDL concentration in terms of the cholesterol contained in this lipoprotein
The method requires measurement of the concentrations of plasma total cholesterol, triglyceride, and HDL.
This information can be obtained without ultracentrifugation and requires only routine lipid analyses in addition to a rapid precipitation of all plasma lipoproteins other than HDL.
Two observations are used in the calculation.
One is that the ratio of the mass of triglyceride to that of of cholesterol in VLDL is apparently.