Tregs, as stable cellular
components of the tumor microenvironment playing a basic role
in tumor immune suppression, have been intensively investigated as
prognostic factors in patient survival and therapy response. However,
findings are quite discrepant with some studies reporting no prognostic
value of Tregs, others stating that increased Treg infiltration correlates
with poor prognosis, or, in contrary, with good prognosis. Recently
deLeeuw et al