Despite the widespread and increasing use of assisted reproductive technologies, there are few prospective studies published addressing the obstetric and pediatric outcomes with these therapies. Additionally, studies suggesting an increase in adverse outcomes such as congenital malformations are limited by small numbers and limited information on confounding variables.9 A recent meta-analysis of a large number of IVF pregnancies suggested that such pregnancies are at increased risk for adverse perinatal outcome, including preterm delivery, low birthweight, placenta previa, gestational diabetes, preeclampsia, and neonatal intensive care admission.9 The main strength of our study is that it incorporated a large number of ART pregnancies and collected prospectively from the general population, with appropriate controls. Our findings corroborate those of the recent meta-analysis, demonstrating a significant increase in hypertensive disorders, placental abnormalities such as placenta previa and placental abruption, and the incidence of cesarean delivery.