household products and disinfectant (OSHA, 2011). According to Laboratory Disinfectant fact sheet, the dilution recommended for Formaldehyde is between 0.2 – 8% to react as an active compound against microorganisms. HISKA® which is the coagulant and density enhancer for rubber latex was used to determine the ability to inhibit the growth of microbe that may also odor eliminator of natural rubber. In order to monitor the volatile component of odor, SPME/GC-MS analysis was done to measure qualitatively the effectiveness of rubber odor elimination by using the antimicrobial substances. In the other hand, an antimicrobial study was also performed to ensure the ability to kill or inhibit the microbe responsible to cause odor.