Plasmodiums are protozoa that may infect various hosts. Only five species are now recognized as
naturally parasitizing humans: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium
ovale and Plasmodium knowlesi. This fifth species, P. knowlesi, previously identified as naturally
parasitizing the monkey Macaca fascicularis, has been microscopically confused for a long time with P.
malariae or P. falciparum and it was not possible to correctly differentiate them until the advent of
molecular biology. To date, natural human infections with P. knowlesi only occur in Southeast Asia and a
similar phenomenon of natural transmission of simian plasmodium to humans has not been reported
elsewhere. This study was conducted to investigate a possible transmission of African small monkey's
plasmodium to humans in populations living near the rainforest of the Democratic Republic of Congo
(DRC) where several species of non-human primates are living. Two successive real-time PCRs were
identified in the literature and used in combination for purpose. Only P. falciparum was found in this
study. However, studies with larger samples and with more advanced techniques should be conducted.
Plasmodiums are protozoa that may infect various hosts. Only five species are now recognized asnaturally parasitizing humans: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodiumovale and Plasmodium knowlesi. This fifth species, P. knowlesi, previously identified as naturallyparasitizing the monkey Macaca fascicularis, has been microscopically confused for a long time with P.malariae or P. falciparum and it was not possible to correctly differentiate them until the advent ofmolecular biology. To date, natural human infections with P. knowlesi only occur in Southeast Asia and asimilar phenomenon of natural transmission of simian plasmodium to humans has not been reportedelsewhere. This study was conducted to investigate a possible transmission of African small monkey'splasmodium to humans in populations living near the rainforest of the Democratic Republic of Congo(DRC) where several species of non-human primates are living. Two successive real-time PCRs wereidentified in the literature and used in combination for purpose. Only P. falciparum was found in thisstudy. However, studies with larger samples and with more advanced techniques should be conducted.
การแปล กรุณารอสักครู่..
