Personnel Needs
The Dribble-Drive is not for everyone. You need to have very specialized personnel. Your perimeter players must be equally adept at taking the ball to the basket and shooting from beyond the 3-point line. Your post players have to be comfortable catching the ball on the move. If he can shoot the ball a little, that will make you better. If he can put the ball on the floor, you'll have the whole package.
Athletic ability helps, as it does in most aspects of basketball. The Dribble Drive produces a lot of rebounds. If you are able to control the offensive glass, it is difficult for opponents to recover. You also have to be in great shape. The Dribble Drive, because of its aggressiveness tends to wear down its opponents.
The offense can start from any set. The one requirement is that the middle be open. If you are going to have a post player, he should be off the block, opposite the ballhandler and my preference is to put him on the baseline.