This process is currently applied in some industries for producing omega-3 oils with EPA+ DHA mass fractions typically around 50–60%. However, even operating at extremely low pressures (0.1 Pa), required temperatures are moderately high (in the range 140–170 ◦C) and process selectivity is relatively low. In addition, to achieve further increase of EPA+ DHA mass fractions with this technology more
passages are required, causing a substantial reduction in recovery and an increased residence time of EPA and DHA at the process temperatures