In a preliminary investigation of the four studied Aframomum species and compounds isolated from A. arundinaceum, we tested a single concentration of 40 μg/mL for each sample and 20 μg/mL for doxorubicin against the sensitive CCRF-CEM leukemia cell line (Figure 2). The extracts from A. kayserianum and A. alboviolaceum were less active and induced respectively 50.33% and 54.36% growth proliferation of CCRF-CEM cells. Compounds 1, 2, 3, 6 and 7 also induced more than 50% growth of this cell line.