In the preceding chapters, many facets of VLC have been outline demonstrating the promising features of this emerging illumination and communication technology. It is anticipated that VLC will become a familiar facility in the office, on the road (V2V communications) and even in toys (Disney Research). The board range of VLC applications is driving an exponential rise in the require data rate, while the semiconductor industry is keeping pace in developing light sources that could provide necessary high data rate. The high data rate VLC paradigm opens up new opportunities for modulation methods that are being developed to meet the particular requirements of simultaneous illumination and communication. Demodulation of the signal and, hence, extraction of the transmitted information require stringent synchronization. In this chapter, we present four VLC modulation methods: on off keying (OOK), pulse position modulation (PPM), inverse pulse position modulation (IPPM), and variable pulse position modulation (VPPM), and develop expressions this describe the bit error rate (BER) for each method. We provide example for the effect of clock time shift and jitter on the system BER performance for the inverse pulse position modulation (IPPM) method.