Many drugs are designed to mimic or to interfere with the action of natural amine neurotransmitters, exemplified by the amine drugs:
Chlorpheniramine is an antihistamine that helps to relieve allergic disorders due to cold, havy fever, itchy skin, insect bites and stings.
Chlorpromazine is a tranquillizer that sedates without inducing sleep. It is used to relieve anxiety, excitement, restlessness or even mental disorder.
Ephedrine and phenylephrine, as amine hydrochlorides, are used as decongestants.
Amphetamine, methamphetamine, and methcathinone are psychostimulant amines that are listed as controlled substances by the US DEA.
Amitriptyline, imipramine, lofepramine and clomipramine are tricyclic antidepressants and tertiary amines.
Nortriptyline, desipramine, and amoxapine are tricyclic antidepressants and secondary amines. (The tricyclics are grouped by the nature of the final amine group on the side chain.)
Substituted tryptamines and phenethylamines are key basic structures for a large variety of psychedelic drugs.
Opiate analgesics such as morphine, codeine, and heroin are tertiary amines.