The major conflict and theme that is too obvious in this movie it is man versus himself. John Nash is struggling to grasp which is reality and delusions. He is also struggling to keep himself alive by trying to do what he should do as a normal human being and not to be swayed into doingcrazy things that are not real and would do no good to him.Eventually, this showed up when his mental illness struck him again and he was made to choose between what is real, which was his wife screaming at him to believe her, or the imaginary,which was Parcher poking a gun at her wife attempting to shoot at her. At the end of the scene,he finally woke up to reality