Histological sections of digestive gland of Biomphalaria straminea infected and uninfected with Angiostrongylus cantonensis. A (uninfected) showing functionally active region of the digestive gland and with intact tissue cells. B (6th after infection) showing the region of the digestive gland with intense process of cellular disorganization exhibiting a lumen with the presence of amorphous material (lu) and presence of vacuolated area (va). C Granulomatous region (gr) in the cephalopedal mass among the collagen fibrous (cf). D Peripheral area of the gland digestive showing a vacuolated area and granulomatous region evidenced by Gomori Trichome stain (gr). Scale bar ¼ 100 mm A, B and 50 mm C, D.