Abstract Diuretics are a mainstay of therapy in dogs with heart failure. In dogs
with advanced heart failure, moderate to high doses of loop diuretics such as furosemide
are used with diminishing effects as profound activation of neuroendocrine
systems promote signs of congestive heart failure. The loop diuretic torsemide has
several characteristics that make it suitable for treatment of advanced heart
failure including longer half-life, increased potency of diuretic action, and antialdosterone
effects. This case report details the administration of torsemide in 3
dogs with advanced heart failure and apparent furosemide resistance.
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