Check out this conversation:
http://www.adobeforums.com/webx/.59b5295b
I was able to get mine open when I held down the shift key and double clicked on the program icon. I still don't understand how to disable to the corrupted plugins, but at least I know it's that now.
This conversation should guide you in the right direction to fixing your problem
Source:
http://www.adobeforums.com/webx/.59b5295b