The same amount of MIC and MBC obtained from this plant against Propionibacterium acnes suggested that Garcinia mangostana extract could possibly act as a bactericidal agent to this microorganism. In addition, the Houttuynia cordata extract also showed good antimicrobial effects against Propionibacterium acnes with a MIC of 0.039 mg/ml but a high concentration was required to kill both Propionibacterium acnes and Staphylococcus epidermidis as compared to the Garcinia mangostana extract.