The apomorphine-induced stereotypies were measured by a score scale (from 0 to 6 where 0 = asleep or stationary; 1 = active; 2 = predominantly active but with bursts of stereotyped sniffing and rearing; 3 = constant stereotyped activity such as sniffing, rearing or head bobbing, but with locomotor activity still present; 4 = constant stereotyped activity maintained in one location; 5 = constant stereotyped activity but with bursts of licking and/or gnawing and biting; and 6 = continual licking and or gnawing of cage grids) after the application of apomorphine (20 mg/kg). Each animal was observed for 10 s intervals every 10 min for 60 min. The results were expressed as the mean sum of scores that were obtained for each group.