Lamina propria consisted of fine network of collagen bundles.
Fibroblasts and blood vessels are also present of control group A.
The present study was conducted on 52 albino Wistar rats of 180-
200 g weight. These animals were randomly divided into four groups
with 13 animals in each group using random number generator. All the
animals in these 4 groups gained weight but no significant differences in
weight were observed among the study groups, hence imposing no
effect on the outcome of the study. All the subjects of each group were
sacrificed after 12 weeks.
Collagen fibers were observed normal in all 13 (100%) animals of
group A (figure 1 and 2) and C (figure 3 and 4), while in Group B, 13
were abnormal i.e. hyalinization and congestion of collagen fibers were
observed (figure 5, 6 and 7) and in group D the collagen fibers were
normal in 10 (76.9%) animals only (figure 8 and 9).
In group A (figure land 2) and C (figure 3 and 4), hyalinization of
collagen fibers and fibrosis were absent in all 13 (100%) animals, while
in Group B hyalinization of collagen fibers (figure 6 and 7) and fibrosis
(figure 5) were present in 13 (100%) animals and in group D the hyalinization
of collagen fibers (figure 10 and 11) and fibrosis (figure 11)were present in 3 (23.1%) animals only (table 2 and 3).