Negative temperatures could be used to create heat engines — engines that convert heat energy to mechanical work, such as combustion engines — that are more than 100-percent efficient, something seemingly impossible. Such engines would essentially not only absorb energy from hotter substances, but also colder ones. As such, the work the engine performed could be larger than the energy taken from the hotter substance alone.
Negative temperatures might also help shed light on one of the greatest mysteries in science. Scientists had expected the gravitational pull of matter to slow down the universe's expansion after the Big Bang, eventually bringing it to a dead stop or even reversing it for a "Big Crunch." However, the universe's expansion is apparently speeding up, accelerated growth that cosmologists suggest may be due to dark energy, an as-yet-unknown substance that could make up more than 70 percent of the cosmos.
In much the same way, the negative pressure of the cold gas the researchers created should make it collapse. However, its negative temperature keeps it from doing so. As such, negative temperatures might have interesting parallels with dark energy that may help scientists understand this enigma.