However, the spice trade was not a long lasting relationship, due to the monopoly system and Christian dissemination. One of the very well known missionaries, Francis Xavier, arrived in Ternate in 1547, with his eagerness; he visited islands in Maluku Island, to spread religion. The relationship between Portuguese and Ternate ended in 1570, the war with Sultan Babullah took five years to be ceased, it was in 1570 to 1575, had forced Portuguese to leave Ternate and been thrown away to Ambon and Tidore.