where A corresponds to the carbon natural abundance,i.e.0.01108. (M0þ1/M0)nat and (M0þ2/M0)nat are the ratio of the integrated peak are as of m/z 61-to-m/z 60 and m/z 62-to-m/z 60 of acetate at natural abundance, respectively.
(M0þ1/M0)sample and (M0þ2/M0)sample are the ratio of the integrated peak are as of m/z 61-to-m/z 60 and m/z 62-to-m/z 60 of 13C enriched acetate samples, respectively.
Eqs. (2) and (3) are transformed to Eqs. (4) and (5) with two unknown variables for solving the TTR (M0þ1) and TTR (M0þ2), respectively. UsingEqs. (4) and(5), the solutions to TTR (M0þ1) and TTR (M0þ2) were given in Eqs. (6) and(7), respectively.
where A corresponds to the carbon natural abundance,i.e.0.01108. (M0þ1/M0)nat and (M0þ2/M0)nat are the ratio of the integrated peak are as of m/z 61-to-m/z 60 and m/z 62-to-m/z 60 of acetate at natural abundance, respectively. (M0þ1/M0)sample and (M0þ2/M0)sample are the ratio of the integrated peak are as of m/z 61-to-m/z 60 and m/z 62-to-m/z 60 of 13C enriched acetate samples, respectively. Eqs. (2) and (3) are transformed to Eqs. (4) and (5) with two unknown variables for solving the TTR (M0þ1) and TTR (M0þ2), respectively. UsingEqs. (4) and(5), the solutions to TTR (M0þ1) and TTR (M0þ2) were given in Eqs. (6) and(7), respectively.
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