In the SOS-chromotest (Table 1), the mean induction factor of the extract was approximately one, with and without S9 mix, demonstrating that the extract did not induced DNA repair at a frequency greater than the blank.
These results do not reveal any genotoxic potential associated with the noni seed extract.
The SOSchromotest results have a high level of agreement (86%) with those from the reverse mutation assay.
Therefore, the SOS-chromotest has some utility in predicting potential mutagenicity, in addition to primary DNA damage.