Selection of appropriate practices alternatives is critical for making the best use of resources. time, and money to facilitate sustainable supply chain management in this study, we propose an integrated framework based on interpretive structural modeling (ISM) and analytic net work process to evaluate potential alternatives for sustainable supply chain management. The criteria used for evaluation are various enablers af sustainability, which are developed along economic, environmental, and social dimensions. ISM is employed to model the relationship among the various enablers. Sensitivity analysis is performed to determine the influences of dimensions, criteria, and alternatives scores an the stability of the ranking results. The re- sults of our study demonstrate that governmental regulations, rewards and incentives, and listening to the views of the customers are the main enablers that can achieve sustainability in supply chains, From the perspective of alternatives, carbon taxing, management training far corporate sustainability, employee training programs on sustainability, and incentives for collaboration in sustainability have the top scores.