A low to normal
DLCO in obesity may represent a loss of pulmonary capillary
bed (as seen with atelectasis), especially at high BMIs
[20]. In this study, obese COPD patients showed an insignificant
increase of percent of predicted of FEV1, FVC,
FEV1/FVC, PEFR, FEF25–75%, DLCO after weight reduction,
but percent of predicted of FRC, ERV and RV were significantly
increased after weight reduction. In contrast, percent
of predicted of IC was significantly decreased.
A low to normalDLCO in obesity may represent a loss of pulmonary capillarybed (as seen with atelectasis), especially at high BMIs[20]. In this study, obese COPD patients showed an insignificantincrease of percent of predicted of FEV1, FVC,FEV1/FVC, PEFR, FEF25–75%, DLCO after weight reduction,but percent of predicted of FRC, ERV and RV were significantlyincreased after weight reduction. In contrast, percentof predicted of IC was significantly decreased.
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