TILLING has come
to refer to the general process of detecting induced
polymorphism, whether by nuclease cleavage,
dHLPC, high resolution
melting , or sequencing. For clarity in this review,
TILLING will refer to detection through mismatchspecific
nuclease cleavage, which was used for all
TILLING screens shown in Table 1. EcoTILLING
is a technically similar approach that has been used
to identify natural polymorphisms in target genes
of melon, bean, sunflower, and peppers.