She is the daughter of Esther Wojcicki, an educator of Russian Jewish descent, and Stanley Wojcicki, a Polish American physics professor at Stanford University. She has 2 sisters: Janet Wojcicki, (PhD, anthropologist and epidemiologist)[4] and Anne Wojcicki, founder of 23andMe. She grew up on the Stanford campus, with George Dantzig as a neighbor.[5] She attended Gunn High School in Palo Alto, California, and wrote for the school newspaper.[6]
Wojcicki studied history and literature at Harvard University and graduated with honors in 1990. She originally planned on getting a PhD in economics and going into academics, but changed her plans when she discovered technology.[5]
She also received her Master's of Science in economics from the University of California, Santa Cruz in 1993 and a Master's in Business Administration from the UCLA Anderson School of Management in 1998.[7]