Previous studies indicated that lignan glycosides possess lower
radical scavenging activity compared to their corresponding aglycones
(Kang et al., 1999). Shyu and Hwang (2002) also reported
that sesaminol triglucoside did not show good antioxidant activity
as assessed by DPPH radical scavenging and LDL oxidation. However,
our results showed that supplementary butanol extracts
ORAC was correlated to sesaminol triglucoside content (Fig. 5B
and Supplementary data 3). Therefore, sesaminol triglucoside,
which is more hydrophilic than sesaminol, apparently will not
react appropriately in hydrophobic medium, such as that used
for DPPH radical scavenging assay, while it will react well with
AAPH-induced radicals in the ORAC method.
Previous studies indicated that lignan glycosides possess lowerradical scavenging activity compared to their corresponding aglycones(Kang et al., 1999). Shyu and Hwang (2002) also reportedthat sesaminol triglucoside did not show good antioxidant activityas assessed by DPPH radical scavenging and LDL oxidation. However,our results showed that supplementary butanol extractsORAC was correlated to sesaminol triglucoside content (Fig. 5Band Supplementary data 3). Therefore, sesaminol triglucoside,which is more hydrophilic than sesaminol, apparently will notreact appropriately in hydrophobic medium, such as that usedfor DPPH radical scavenging assay, while it will react well withAAPH-induced radicals in the ORAC method.
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