The high school that participated in this survey was one of the most reputed schools in Ankara, Turkey’s capital city. The sociocultural level of the study population was high, as most of the students’ parents had university degrees. Education is associated with more positive views about organ donation and transplantation. After the students finished our training program, we found that a significantly higher proportion said they would consent to donate their own organs. Also, a lower proportion said that they absolutely opposed donation. Additionally, after the program, a significantly higher percentage of students said they would approve donating an organ from a brain-dead relative. Prior to training, the main reasons for refusing personal donation were religious beliefs, suspicion about inappropriate use of harvested organs, disfigurement of the body, fear of the actual procurement process, and lack of information about the donation process. After training, we observed lower frequencies of all of these responses. The students’ knowledge of the major organs and tissues that can currently be transplanted was also significantly better after the educational program. Significantly, more respondents picked the correct answer for the definitions of brain-death and transplantation after the training.