Curative oncologic treatment beyond removal of
explanted lung in stage I disease was offered based on stage
and site of disease, and included lobectomy, radiation,
sequential radiation followed by chemotherapy, and
adjuvant chemotherapy. Lobectomy was performed in a
patient with T2N1M0, stage II lung cancer in remaining
native lung; however, this patient developed metastases
5 months later, and died 7 months after chemotherapy
was initiated. Sequential radiation (50 Gy in 5 fractions)
followed by chemotherapy was delivered to two patients
with cancer in transplanted lung (one with stage I small cell
lung cancer, and the other with stage II NSCLC disease).
Adjuvant chemotherapy was administered in 2 out of 3
patients with stage II disease in explanted lung.