These developments have provided the basis of several large-scale homogeneous bulk industrial processes. Examples are the Rh-based carbonylation of methanol and hydroformylation processes. More recently we see the development of metathesis applied, for instance, in the ring-opening polymerization process of Huels, and enantiomeric catalysis due to invention of highly enantiomeric ligand systems, as for the production L-Dopa by Monsanto.