Introduction: Lichen simplex chronicus (LSC) is an eczematous skin disease characterized by
single or a few thickened and 'lichenified' skin plaques, with very disturbing itching. The role
of psychological factors and transient relief of pruritus after violent scratching seems to be of
great importance in development and perpetuation of its course. On the other hand, the
chronic nuisance itching may lead to burdensome psychological distress and impaired
quality of life.
Aim: This study sought to elucidate more aspects of this interplay.
Material and methods: 40 patients with LSC (diagnosed clinically) and 40 healthy controls
(selected between attendants of the patients with no skin problem) were enrolled in this
study. Hamilton questionnaire and symptom checklist 90-revised (SCL-90 R) were filled by a
psychologist for all cases. Demographic characteristics, localization of the skin lesions,
personal and family history of psychiatric disorders (if existent) were recorded.
Results and discussion: Mean scores of SCL-90-R in somatization, interpersonal sensitivity,
depression, anxiety, aggression, and phobia items were significantly higher in patient group
than control group. Regarding Hamilton depression test, the mean scores were higher in
patient group, but the difference was not statically significant.
Conclusions: Patients with LSC are subject to ample psychiatric morbidities. Close collaboration
of dermatologist and psychiatrist is essential in its successful control.