Boeing will open a plant in China in partnership with state-owned Commercial Aircraft Corporation of China (Comac).
The plan to open a plant in China has received criticism from the head of Boeing's biggest union and Donald Trump, who is seeking nomination as the Republican candidate in the 2016 presidential election.
he new factory will focus on painting and assembling twin-engine 737 aircraft manufactured in the US.
Chinese firms also agreed to buy 300 Boeing jets, in deals worth about $38bn (£25bn).