The subjects were followed from the date of the acceptance
of the baseline survey through December 31, 1999.
Since the information of the resident register is open to
the general public under the resident registration law,
investigators confirmed yearly residence status and survival
with using residential registers, kept by a public
health center in each of the study areas. Residency and
death registration is required by Family Registration Law
in Japan, and was believed to be complete across Japan.
Death certificate diagnoses were provided by the Ministry
of Health and Labor under permission from Welfare after
Ministry of Internal Affairs and Communications granted
permission. The underlying causes of deaths were defined
according to the International Classification of Diseases,
9th Revision from 1988 to 1994, and 10th Revision from
1995 to 1999 for the National Vital Statistics. Therefore,
all deaths that occurred in the cohort were confirmed by
death certificates from a public health center, except for
subjects who died after they moved from their original
community, in which case the subject was treated as a censored
case. The average follow-up period for the participants
was 9.9 years. The Ethical Committees of the
Nagoya University School of Medicine and the University
of Tsukuba approved the present study
The subjects were followed from the date of the acceptanceof the baseline survey through December 31, 1999.Since the information of the resident register is open tothe general public under the resident registration law,investigators confirmed yearly residence status and survivalwith using residential registers, kept by a publichealth center in each of the study areas. Residency anddeath registration is required by Family Registration Lawin Japan, and was believed to be complete across Japan.Death certificate diagnoses were provided by the Ministryof Health and Labor under permission from Welfare afterMinistry of Internal Affairs and Communications grantedpermission. The underlying causes of deaths were definedaccording to the International Classification of Diseases,9th Revision from 1988 to 1994, and 10th Revision from1995 to 1999 for the National Vital Statistics. Therefore,all deaths that occurred in the cohort were confirmed bydeath certificates from a public health center, except forsubjects who died after they moved from their originalcommunity, in which case the subject was treated as a censoredcase. The average follow-up period for the participantswas 9.9 years. The Ethical Committees of theNagoya University School of Medicine and the Universityof Tsukuba approved the present study
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