When Amaranth (0.5 ml of a 0.1% solution) was injected under the skin of rats twice a week for 365 days, no tumor growth was observed. When 0.2% of amaranth in feed (average 0.1 g/kg/day) was fed to rats for 417 days, no induction of tumors was observed, but when feeding was continued for an additional 830 days, one case of intestinal cancer was observed. The FAO/WHO special committee determined its ADI as 0-1.5 mg/kg.