In another report, Manivannan et al. (2011) screened some selected brown seaweed from Vedalai coastal waters, Gukf of Mannar. Methanol extract of the brown seaweed species were reported to exhibit strongest antibacterial activity and the least by chloroform and petroleum ether. This agrees with our findings in which methanol extract had the highest antibacterial activity and the least was observed in chloroform and ethyl acetate extract. Likewise, Yuvaraj, Sreedevi, Amruth Raghu, and Shankar (2011) revealed that methanol extracts of crude form of C.glomerata has a broad spectrum over V. fischeri and V. vulnificus than other extracts. In the present study methanol extract of S. plagyophillum shows promising results against B. subtilis. Selvi, Selvaraj, and chidambaram (2001) screened around 20 algae along Idinthakarai coast using methanol and ethanol. B. subtilis and staphylococcus sp. were reported to be highly susceptible to most of the algal extracts which is in agreement with the present investigation that methanol extract shows activity for both S. aureus and B. subtilis.